MicroRNA-20a constrains p300-driven myocardial angiogenic transcription by direct targeting of p300.

MicroRNA-20a constrains p300-driven myocardial angiogenic transcription by direct targeting of p300.

To characterize downstream effectors of p300 acetyltransferase in the myocardium.Acetyltransferase p300 is a central driver of the hypertrophic response to increased workload, but its biological targets and downstream effectors are incompletely known.Mice expressing a myocyte-restricted transgene en...

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Bibliographic Details
Main Authors: Lina A Shehadeh, Salil Sharma, Mônica Pessanha, Jian Qin Wei, Jing Liu, Huijun Yuan, Claudia O Rodrigues, Michaela Scherr, Nicholas F Tsinoremas, Nanette H Bishopric
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827282?pdf=render

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http://europepmc.org/articles/PMC3827282?pdf=render

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