Reprogramming viral immune evasion for a rational design of next-generation vaccines for RNA viruses

Reprogramming viral immune evasion for a rational design of next-generation vaccines for RNA viruses

Type I interferons (IFNs-α/β) are antiviral cytokines that constitute the innate immunity of hosts to fight against viral infections. Recent studies, however, have revealed the pleiotropic functions of IFNs, in addition to their antiviral activities, for the priming of activation and maturation of a...

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Bibliographic Details
Main Authors: Chia-Ming Su, Yijun Du, Raymond R. R. Rowland, Qiuhong Wang, Dongwan Yoo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
type I interferons (IFNs)
NF-kappa B (NF-κB)
IFN antagonism
live-attenuated vaccine
veterinary vaccine
viral immune evasion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172000/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172000/full

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