Vancomycin-Loaded Collagen/Hydroxyapatite Layers Electrospun on 3D Printed Titanium Implants Prevent Bone Destruction Associated with <i>S. epidermidis</i> Infection and Enhance Osseointegration

Vancomycin-Loaded Collagen/Hydroxyapatite Layers Electrospun on 3D Printed Titanium Implants Prevent Bone Destruction Associated with <i>S. epidermidis</i> Infection and Enhance Osseointegration

The aim of the study was to develop an orthopedic implant coating in the form of vancomycin-loaded collagen/hydroxyapatite layers (COLHA+V) that combine the ability to prevent bone infection with the ability to promote enhanced osseointegration. The ability to prevent bone infection was investigated...

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Bibliographic Details
Main Authors: Tomáš Suchý, Lucie Vištejnová, Monika Šupová, Pavel Klein, Martin Bartoš, Yaroslav Kolinko, Tereza Blassová, Zbyněk Tonar, Marek Pokorný, Zbyněk Sucharda, Margit Žaloudková, František Denk, Rastislav Ballay, Štefan Juhás, Jana Juhásová, Eva Klapková, Lukáš Horný, Radek Sedláček, Tomáš Grus, Zdeněk Čejka, Kateřina Chudějová, Jaroslav Hrabák
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
orthopedic implant
collagen
hydroxyapatite
vancomycin
implant-related bone infection
<i>Staphylococcus epidermidis</i>
Online Access:https://www.mdpi.com/2227-9059/9/5/531

Internet

https://www.mdpi.com/2227-9059/9/5/531

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