Anti-Leukemic Properties of Aplysinopsin Derivative EE-84 Alone and Combined to BH3 Mimetic A-1210477

Aplysinopsins are a class of marine indole alkaloids that exhibit a wide range of biological activities. Although both the indole and N-benzyl moieties of aplysinopsins are known to possess antiproliferative activity against cancer cells, their mechanism of action remains unclear. Through in vitro a...

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Bibliographic Details
Main Authors: Sungmi Song, Sua Kim, Eslam R. El-Sawy, Claudia Cerella, Barbora Orlikova-Boyer, Gilbert Kirsch, Christo Christov, Mario Dicato, Marc Diederich
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/19/6/285