Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells

Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells

HIV transmission via genital and colorectal mucosa are the most common routes of dissemination. Here, we explored the effects of free and complement-opsonized HIV on colorectal tissue. Initially, there was higher antiviral responses in the free HIV compared to complement-opsonized virus. The mucosal...

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Bibliographic Details
Main Authors: Pradyot Bhattacharya, Rada Ellegård, Mohammad Khalid, Cecilia Svanberg, Melissa Govender, Åsa V Keita, Johan D Söderholm, Pär Myrelid, Esaki M Shankar, Sofia Nyström, Marie Larsson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
HIV
colorectal mucosa
virus infection
t lymphocytes
innnate responses
Online Access:https://elifesciences.org/articles/57869

Internet

https://elifesciences.org/articles/57869

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