Targeting Induced Local Lesions in the Wheat DEMETER and DRE2 Genes, Responsible for Transcriptional Derepression of Wheat Gluten Proteins in the Developing Endosperm

Wheat is a major source of energy and nutrition worldwide, but it is also a primary cause of frequent diet-induced health issues, specifically celiac disease, for which the only effective therapy so far is strict dietary abstinence from gluten-containing grains. Wheat gluten proteins are grouped int...

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Main Authors: Nuan Wen, Claudia E. Osorio, Rhoda A. T. Brew-Appiah, Jaime H. Mejías, Tariq Alam, Samneet Kashyap, Steffen Reinbothe, Christiane Reinbothe, Charles P. Moehs, Diter von Wettstein, Sachin Rustgi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.847635/full