Targeting Induced Local Lesions in the Wheat DEMETER and DRE2 Genes, Responsible for Transcriptional Derepression of Wheat Gluten Proteins in the Developing Endosperm

Targeting Induced Local Lesions in the Wheat DEMETER and DRE2 Genes, Responsible for Transcriptional Derepression of Wheat Gluten Proteins in the Developing Endosperm

Wheat is a major source of energy and nutrition worldwide, but it is also a primary cause of frequent diet-induced health issues, specifically celiac disease, for which the only effective therapy so far is strict dietary abstinence from gluten-containing grains. Wheat gluten proteins are grouped int...

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Bibliographic Details
Main Authors: Nuan Wen, Claudia E. Osorio, Rhoda A. T. Brew-Appiah, Jaime H. Mejías, Tariq Alam, Samneet Kashyap, Steffen Reinbothe, Christiane Reinbothe, Charles P. Moehs, Diter von Wettstein, Sachin Rustgi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Nutrition
Subjects:
wheat
celiac disease
gluten
epitope
reduced immunogenicity
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.847635/full

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