CD40L and Its Receptors in Atherothrombosis—An Update
CD40L (CD154), a member of the tumor necrosis factor superfamily, is a co-stimulatory molecule that was first discovered on activated T cells. Beyond its fundamental role in adaptive immunity—ligation of CD40L to its receptor CD40 is a prerequisite for B cell activation and antibody production—evide...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-06-01
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Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fcvm.2017.00040/full |