CD40L and Its Receptors in Atherothrombosis—An Update

CD40L (CD154), a member of the tumor necrosis factor superfamily, is a co-stimulatory molecule that was first discovered on activated T cells. Beyond its fundamental role in adaptive immunity—ligation of CD40L to its receptor CD40 is a prerequisite for B cell activation and antibody production—evide...

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Bibliographic Details
Main Authors: Nathaly Anto Michel, Andreas Zirlik, Dennis Wolf
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcvm.2017.00040/full