Candida-induced granulocytic myeloid-derived suppressor cells are protective against polymicrobial sepsis

ABSTRACT Polymicrobial intra-abdominal infections (IAI) can lead to life-threatening sepsis with significant morbidity and mortality, especially when pathogenic fungi are involved. We have employed an established clinically relevant mouse model of fungal/bacterial IAI and shown that immunization wit...

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Bibliographic Details
Main Authors: Shannon Esher Righi, Amanda J. Harriett, Elizabeth A. Lilly, Paul L. Fidel, Mairi C. Noverr
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.01446-23