Development of Allosteric Ribozymes for ATP and <span style="font-variant: small-caps">l</span>-Histidine Based on the R3C Ligase Ribozyme
During the evolution of the RNA, short RNAs are thought to have joined together to form long RNAs, enhancing their function as ribozymes. Previously, the artificial R3C ligase ribozyme (73 nucleotides) was successfully reduced to 46 nucleotides; however, its activity decreased significantly. Therefo...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-04-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/14/4/520 |