Development of Allosteric Ribozymes for ATP and <span style="font-variant: small-caps">l</span>-Histidine Based on the R3C Ligase Ribozyme

During the evolution of the RNA, short RNAs are thought to have joined together to form long RNAs, enhancing their function as ribozymes. Previously, the artificial R3C ligase ribozyme (73 nucleotides) was successfully reduced to 46 nucleotides; however, its activity decreased significantly. Therefo...

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Bibliographic Details
Main Authors: Yuna Akatsu, Hiromi Mutsuro-Aoki, Koji Tamura
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/14/4/520