A transcriptomic analysis in mice following a single dose of ibogaine identifies new potential therapeutic targets

Abstract Ibogaine (IBO) is an atypical psychedelic with a complex mechanism of action. To date, the mechanisms that may underlie its anti-addictive effects are still not defined. This study aims to identify changes in gene expression induced by a single oral dose of IBO in the cortex of mice by mean...

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Bibliographic Details
Main Authors: Judit Biosca-Brull, Genis Ona, Lineth Alarcón-Franco, Maria Teresa Colomina
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02773-7