PI3K-C2α Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation

Insulin resistance is a syndrome that affects multiple insulin target tissues, each having different biological functions regulated by insulin. A remaining question is to mechanistically explain how an insulin target cell/tissue can be insulin resistant in one biological function and insulin sensiti...

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Bibliographic Details
Main Authors: Barbara Leibiger, Tilo Moede, Meike Paschen, Na-Oh Yunn, Jong Hoon Lim, Sung Ho Ryu, Teresa Pereira, Per-Olof Berggren, Ingo B. Leibiger
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009559