A One-Pot Six-Component Reaction for the Synthesis of 1,5-Disubstituted Tetrazol-1,2,3-Triazole Hybrids and Their Cytotoxic Activity against the MCF-7 Cell Line

A One-Pot Six-Component Reaction for the Synthesis of 1,5-Disubstituted Tetrazol-1,2,3-Triazole Hybrids and Their Cytotoxic Activity against the MCF-7 Cell Line

A high-order multicomponent reaction involving a six-component reaction to obtain the novel linked 1,5-disubstituted tetrazole-1,2,3-triazole hybrids in low to moderate yield is described. This one-pot reaction is carried out under a cascade process consisting of three sequential reactions: Ugi-azid...

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Bibliographic Details
Main Authors: Cesia M. Aguilar-Morales, Jorge Gustavo Araujo-Huitrado, Yamilé López-Hernández, Claudia Contreras-Celedón, Alejandro Islas-Jácome, Angelica Judith Granados-López, Cesar R. Solorio-Alvarado, Jesús Adrián López, Luis Chacón-García, Carlos J. Cortés-García
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
Ugi-azide
high-order multicomponent reaction
1,5-disubstituted tetrazole
1,4-disubstituted-1,2,3-triazoles
hybrid compounds
cytotoxic activity
Online Access:https://www.mdpi.com/1420-3049/26/20/6104

Internet

https://www.mdpi.com/1420-3049/26/20/6104

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