Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets

Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets

Abstract Background Dissolution of artemether (ART) and lumefantrine (LUM) active pharmaceutical ingredients (APIs) in fixed dose combination (FDC) ART/LUM tablets is one of the critical quality attributes. Thus, the verification of the release profile of ART and LUM from FDC ART/LUM tablets using a...

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Bibliographic Details
Main Authors: Sileshi Belew, Sultan Suleman, Markos Duguma, Henok Teshome, Evelien Wynendaele, Luc Duchateau, Bart De Spiegeleer
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Malaria Journal
Subjects:
Artemether
Dissolution
In-vitro
Lumefantrine
Online Access:http://link.springer.com/article/10.1186/s12936-020-03209-5

Internet

http://link.springer.com/article/10.1186/s12936-020-03209-5

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