Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Early life stress has been associated with the occurrence of gastrointestinal diseases later in life, but underlying mechanisms remain poorly understood. Here, Wong et al. show that early life stress leads to expansion of intestinal stem cells and their differentiation into serotonin-producing enter...

Full description

Bibliographic Details
Main Authors: Hoi Leong Xavier Wong, Hong-yan Qin, Siu Wai Tsang, Xiao Zuo, Sijia Che, Chi Fung Willis Chow, Xi Li, Hai-tao Xiao, Ling Zhao, Tao Huang, Cheng Yuan Lin, Hiu Yee Kwan, Tao Yang, Frank M. Longo, Aiping Lyu, Zhao-xiang Bian
Format: Article
Language:English
Published: Nature Portfolio 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09744-3

Internet

https://doi.org/10.1038/s41467-019-09744-3

Similar Items