Molecular Model of Plasma PAF Acetylhydrolase-Lipoprotein Association: Insights from the Structure

Plasma platelet-activating factor acetylhydrolase (PAF-AH), also called lipoprotein-associated phospholipase A2 (Lp-PLA2), is a group VIIA PLA2 enzyme that catalyzes the hydrolysis of PAF and certain oxidized phospholipids. Although the role of PAF-AH as a pro- or anti-atherosclerotic enzyme is high...

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Bibliographic Details
Main Authors: Brian J. Bahnson, Prabhavathi Srinivasan
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/3/541/