Pharmacokinetics, bioavailability, metabolism and excretion of δ-viniferin in rats

A highly rapid and sensitive liquid chromatographic–electrospray ionization tandem mass spectrometric (LC–ESI-MS/MS) method was developed and validated for the determination of trans-δ-viniferin (Rs-1) in rat plasma, urine and feces. All biological samples were prepared by liquid–liquid extraction a...

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Bibliographic Details
Main Authors: Ping Mao, Yinping Lei, Tingting Zhang, Chen Ma, Bo Jin, Tong Li
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383516300442