Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer or Suspected Related Hereditary Syndromes: Historical Prospective Analysis

Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer or Suspected Related Hereditary Syndromes: Historical Prospective Analysis

We investigate the prevalence of germline mutations in cancer predisposition genes in patients with pancreatic ductal adenocarcinoma (PDAC) or suspected related hereditary syndromes. Methods: we enrolled for NGS with an Illumina TrueSight Cancer panel comprising 19 CPGs and 113 consecutive subjects...

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Bibliographic Details
Main Authors: Arianna Dal Buono, Laura Poliani, Luana Greco, Paolo Bianchi, Monica Barile, Valentina Giatti, Cristiana Bonifacio, Silvia Carrara, Alberto Malesci, Luigi Laghi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
pancreatic cancer
hereditary syndrome
pathogenic variant
germline mutation
cancer predisposition
Online Access:https://www.mdpi.com/2072-6694/15/6/1852

Internet

https://www.mdpi.com/2072-6694/15/6/1852

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