Gamma Delta T-Cell Based Cancer Immunotherapy: Past-Present-Future

γδ T-cells directly recognize and kill transformed cells independently of HLA-antigen presentation, which makes them a highly promising effector cell compartment for cancer immunotherapy. Novel γδ T-cell-based immunotherapies, primarily focusing on the two major γδ T-cell subtypes that infiltrate tu...

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Bibliographic Details
Main Authors: José Saura-Esteller, Milon de Jong, Lisa A. King, Erik Ensing, Benjamin Winograd, Tanja D. de Gruijl, Paul W. H. I. Parren, Hans J. van der Vliet
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.915837/full