Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic Inducers

The quinoxaline scaffold is a promising platform for the discovery of active chemotherapeutic agents. Three series of quinoxaline derivatives were synthesized and biologically evaluated against three tumor cell lines (HCT116 human colon carcinoma, HepG2, liver hepatocellular carcinoma and MCF-7, hum...

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Bibliographic Details
Main Authors: Aliya M. S. El Newahie, Yassin M. Nissan, Nasser S. M. Ismail, Dalal A. Abou El Ella, Sohair M. Khojah, Khaled A.M. Abouzid
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/6/1175