Heritability Estimation of Multiple Sclerosis Related Plasma Protein Levels in Sardinian Families with Immunochip Genotyping Data

Heritability Estimation of Multiple Sclerosis Related Plasma Protein Levels in Sardinian Families with Immunochip Genotyping Data

This work aimed at estimating narrow-sense heritability, defined as the proportion of the phenotypic variance explained by the sum of additive genetic effects, via Haseman–Elston regression for a subset of 56 plasma protein levels related to Multiple Sclerosis (MS). These were measured in 212 relate...

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Bibliographic Details
Main Authors: Andrea Nova, Giulia Nicole Baldrighi, Teresa Fazia, Francesca Graziano, Valeria Saddi, Marialuisa Piras, Ashley Beecham, Jacob L. McCauley, Luisa Bernardinelli
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Life
Subjects:
heritability
plasma protein levels
Immunochip SNPs
multiple sclerosis
Online Access:https://www.mdpi.com/2075-1729/12/7/1101

Internet

https://www.mdpi.com/2075-1729/12/7/1101

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