Analysis of the accuracy of Z-scores of non-invasive prenatal testing for fetal Trisomies 13, 18, and 21 that employs the ion proton semiconductor sequencing platform

Analysis of the accuracy of Z-scores of non-invasive prenatal testing for fetal Trisomies 13, 18, and 21 that employs the ion proton semiconductor sequencing platform

Abstract Background Non-invasive prenatal testing (NIPT) is frequently being used to screen for trisomies 13, 18 and 21 for prenatal diagnosis. However, NIPT performs poorly when compared with invasive testing and thus should not be used to diagnose trisomies. The result of NIPT for an individual wo...

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Bibliographic Details
Main Authors: Yuan Tian, Linlin Zhang, Weifang Tian, Jinshuang Gao, Liting Jia, Shihong Cui
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Molecular Cytogenetics
Subjects:
Non-invasive prenatal testing (NIPT)
False positive
Confined placental mosaicism (CPM)
Trisomies
Online Access:http://link.springer.com/article/10.1186/s13039-018-0397-x

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http://link.springer.com/article/10.1186/s13039-018-0397-x

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