Pharmacological Dissection of the Crosstalk between Na<sub>V</sub> and Ca<sub>V</sub> Channels in GH3b6 Cells

Pharmacological Dissection of the Crosstalk between Na<sub>V</sub> and Ca<sub>V</sub> Channels in GH3b6 Cells

Thanks to the crosstalk between Na<sup>+</sup> and Ca<sup>2+</sup> channels, Na<sup>+</sup> and Ca<sup>2+</sup> homeostasis interplay in so-called excitable cells enables the generation of action potential in response to electrical stimulation. Here, w...

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Bibliographic Details
Main Authors: Léa Réthoré, Joohee Park, Jérôme Montnach, Sébastien Nicolas, Joseph Khoury, Elodie Le Seac’h, Kamel Mabrouk, Harold De Pomyers, Hélène Tricoire-Leignel, César Mattei, Daniel Henrion, Ziad Fajloun, Michel De Waard, Claire Legendre, Christian Legros
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
GH3b6 cells
voltage-gated sodium channel
L-type voltage-gated calcium channel
veratridine
patch-clamp
Fura-2
Online Access:https://www.mdpi.com/1422-0067/23/2/827

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https://www.mdpi.com/1422-0067/23/2/827

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