Jujuboside B suppresses angiogenesis and tumor growth via blocking VEGFR2 signaling pathway

Jujuboside B suppresses angiogenesis and tumor growth via blocking VEGFR2 signaling pathway

Jujuboside B (JuB), one of the main active triterpenoid saponins from the traditional Chinese medicine Ziziphus jujuba, possesses a wide range of pharmacological activities. However, it is unknown whether JuB can inhibit tumor angiogenesis, a crucial step in solid tumor growth. In this study, we fou...

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Bibliographic Details
Main Authors: Pan Zhang, Xing Lai, Mao-Hua Zhu, Jiangpei Shi, Hong Pan, Yanhu Huang, Run-Jie Guo, Qin Lu, Chao Fang, Mei Zhao
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Jujuboside B
Triterpenoid saponin
Antiangiogenesis
Chick embryo chorioallantoic membrane
VEGFR2
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023042809

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http://www.sciencedirect.com/science/article/pii/S2405844023042809

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