Nontypeable Haemophilus influenzae Redox Recycling of Protein Thiols Promotes Resistance to Oxidative Killing and Bacterial Survival in Biofilms in a Smoke-Related Infection Model

Nontypeable Haemophilus influenzae Redox Recycling of Protein Thiols Promotes Resistance to Oxidative Killing and Bacterial Survival in Biofilms in a Smoke-Related Infection Model

ABSTRACT Smoke exposure is a risk factor for community-acquired pneumonia, which is typically caused by host-adapted airway opportunists like nontypeable Haemophilus influenzae (NTHi). Genomic analyses of NTHi revealed homologs of enzymes with predicted roles in reduction of protein thiols, which ca...

Full description

Bibliographic Details
Main Authors: Benjamin C. Hunt, Xin Xu, Amit Gaggar, W. Edward Swords
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mSphere
Subjects:
Haemophilus influenzae
bacteria
biofilm
pneumonia
smoking-related infection
Online Access:https://journals.asm.org/doi/10.1128/msphere.00847-21

Internet

https://journals.asm.org/doi/10.1128/msphere.00847-21

Similar Items