Tyrosine Hydroxylase, Vesicular Monoamine Transporter and Dopamine Transporter mRNA Expression in Nigrostriatal Tissue of Rats with Pedunculopontine Neurotoxic Lesion

Tyrosine Hydroxylase, Vesicular Monoamine Transporter and Dopamine Transporter mRNA Expression in Nigrostriatal Tissue of Rats with Pedunculopontine Neurotoxic Lesion

Background: The degeneration of the pedunculopontine nucleus (PPN) precedes the degeneration of the nigral cells in the pre-symptomatic stages of Parkinson’s disease (PD). Although the literature recognizes that a lesion of the PPN increases the vulnerability of dopaminergic cells, it is unknown if...

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Bibliographic Details
Main Authors: Lisette Blanco-Lezcano, Esteban Alberti-Amador, Mei-Li Díaz-Hung, María Elena González-Fraguela, Bárbara Estupiñán-Díaz, Teresa Serrano-Sánchez, Liliana Francis-Turner, Javier Jiménez-Martín, Yamilé Vega-Hurtado, Isabel Fernández-Jiménez
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Behavioral Sciences
Subjects:
pedunculopontine nucleus
substantia nigra pars compacta
tyrosyne hydroxylase
vesicular monoamine transporter 2
dopamine transporter
dopaminergic homeostasis
Online Access:http://www.mdpi.com/2076-328X/8/2/20

Internet

http://www.mdpi.com/2076-328X/8/2/20

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