Mutations in human SARS-CoV-2 spike proteins, potential drug binding and epitope sites for COVID-19 therapeutics development

Mutations in human SARS-CoV-2 spike proteins, potential drug binding and epitope sites for COVID-19 therapeutics development

The comparison of 303,250 human SARS-CoV-2 spike protein sequences with the reference protein sequence Wuhan-Hu-1, showed ∼96.5% of the spike protein sequence has undergone the mutations till date, since outbreak of the COVID-19 pandemic disease that was first reported in December 2019. A total of 1...

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Bibliographic Details
Main Author: Kunchur Guruprasad
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Structural Biology
Subjects:
Human SARS-CoV-2 mutations
Mutation propensity
Invariant sites
Epitope sites
Drug design sites
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X22000022

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http://www.sciencedirect.com/science/article/pii/S2665928X22000022

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