Encapsulation of Metronidazole in Biocompatible Macrocycles and Structural Characterization of Its Nano Spray-Dried Nanostructured Composite

Encapsulation of Metronidazole in Biocompatible Macrocycles and Structural Characterization of Its Nano Spray-Dried Nanostructured Composite

Due to the great potential of biocompatible cucurbit[7]uril (CB7) and 4-sulfonatocalix[4]arene (SCX4) macrocycles in drug delivery, the confinement of the pharmaceutically important metronidazole as an ionizable model drug has been systematically studied in these cavitands. Absorption and fluorescen...

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Bibliographic Details
Main Authors: Mirella Mirankó, Mónika Megyesi, Zsombor Miskolczy, Judit Tóth, Tivadar Feczkó, László Biczók
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
drug delivery
self-assembly
host–guest binding
inclusion complex
spray drying
4-sulfonatocalix[4]arene
Online Access:https://www.mdpi.com/1420-3049/26/23/7335

Internet

https://www.mdpi.com/1420-3049/26/23/7335

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