Tracing the STING exocytosis pathway during herpes viruses infection

ABSTRACTThe STimulator of INterferon Genes (STING) constitutes a major DNA-sensing pathway that restricts HSV-1 infection in different models by activating type I interferon and pro-inflammatory responses. To counteract STING, HSV-1 has evolved numerous strategies including mechanisms to interfere w...

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Bibliographic Details
Main Authors: Christos Dogrammatzis, Rabina Saud, Hope Waisner, Sarah Lasnier, Sreenath Muraleedharan Suma, Brandon Grieshaber, Maria Kalamvoki
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.00373-24