Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models

Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although extensive strides have been made in the treatments for non-diabetic atherosclerosis and its complications, for patients with diabetes, these therapies provide less benefit for protection from cardiovascular d...

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Main Authors: Lander Egaña-Gorroño, Raquel López-Díez, Gautham Yepuri, Lisa S. Ramirez, Sergey Reverdatto, Paul F. Gugger, Alexander Shekhtman, Ravichandran Ramasamy, Ann Marie Schmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2020.00037/full