Transcriptional Regulation of GDF15 by EGR1 Promotes Head and Neck Cancer Progression through a Positive Feedback Loop

Transcriptional Regulation of GDF15 by EGR1 Promotes Head and Neck Cancer Progression through a Positive Feedback Loop

Growth and differentiation factor 15 (GDF15), a divergent member of the transforming growth factor-β (TGF-β) superfamily, has been reported to be overexpressed in different kinds of cancer types. However, the function and mechanism of GDF15 in head and neck cancer (HNC) remains unclear. The Cancer G...

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Bibliographic Details
Main Authors: Yanli Jin, Seung-Nam Jung, Mi Ae Lim, Chan Oh, Yudan Piao, Hae Jong Kim, Lihua Liu, Yea Eun Kang, Jae Won Chang, Ho-Ryun Won, Kunho Song, Bon Seok Koo
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
head and neck cancer
GDF15
EGR1
progression
Online Access:https://www.mdpi.com/1422-0067/22/20/11151

Internet

https://www.mdpi.com/1422-0067/22/20/11151

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