Genetic association-based functional analysis detects HOGA1 as a potential gene involved in fat accumulation

Genetic association-based functional analysis detects HOGA1 as a potential gene involved in fat accumulation

Although there are a number of discoveries from genome-wide association studies (GWAS) for obesity, it has not been successful in linking GWAS results to biology. We sought to discover causal genes for obesity by conducting functional studies on genes detected from genetic association analysis. Gene...

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Bibliographic Details
Main Authors: Myungsuk Kim, Kye Won Park, Yeongseon Ahn, Eun Bi Lim, Soo Heon Kwak, Ahmad Randy, No Joon Song, Kyong Soo Park, Chu Won Nho, Yoon Shin Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
exome sequencing
obesity
association analysis
adipogenesis
HOGA1
3T3-L1
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.951025/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.951025/full

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