Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

Riboswitches are non-coding RNA elements that detect metabolites and control expression by regulating mRNA levels or translation. Here, the authors provide evidence that theE. coli thiC riboswitch has a pause site in the translation initiation region that acts as a checkpoint for thiCexpression.

Bibliographic Details
Main Authors: Adrien Chauvier, Frédéric Picard-Jean, Jean-Christophe Berger-Dancause, Laurène Bastet, Mohammad Reza Naghdi, Audrey Dubé, Pierre Turcotte, Jonathan Perreault, Daniel A. Lafontaine
Format: Article
Language:English
Published: Nature Portfolio 2017-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13892

Internet

https://doi.org/10.1038/ncomms13892

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