In Vitro and Computational Studies of Perezone and Perezone Angelate as Potential Anti-Glioblastoma Multiforme Agents

In Vitro and Computational Studies of Perezone and Perezone Angelate as Potential Anti-Glioblastoma Multiforme Agents

Glioblastoma multiforme (GBM) represents the most malignant type of astrocytoma, with a life expectancy of two years. It has been shown that Poly (ADP-ribose) polymerase 1 (PARP-1) protein is over-expressed in GBM cells, while its expression in healthy tissue is low. In addition, perezone, a phyto-c...

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Bibliographic Details
Main Authors: Maricarmen Hernández-Rodríguez, Pablo I. Mendoza Sánchez, Joel Martínez, Martha E. Macías Pérez, Erika Rosales Cruz, Teresa Żołek, Dorota Maciejewska, René Miranda Ruvalcaba, Elvia Mera Jiménez, María I. Nicolás-Vázquez
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
phyto-compounds
computational studies
drug-likeness
anti-neoplastic activity
glioblastoma multiforme
Online Access:https://www.mdpi.com/1420-3049/27/5/1565

Internet

https://www.mdpi.com/1420-3049/27/5/1565

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