Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats

Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats

Introduction: The pentylenetetrazol (PTZ)-induced kindling model acts through the antagonism of central GABAA receptors and is one of the most widely used experimental animal models to study the characteristics of seizure development, behavioral manifestations and evaluation of antiseizure effects o...

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Bibliographic Details
Main Authors: Zohabia Rehman, Talha Farooq, Sana Javaid, Waseem Ashraf, Muhammad Fawad Rasool, Noreen Samad, Maryam Tariq, Syed Muhammad Muneeb Anjum, Farzane Sivandzade, Faisal Alotaibi, Faleh Alqahtani, Imran Imran
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Saudi Pharmaceutical Journal
Subjects:
Epilepsy
PTZ-kindling
Levetiracetam
Sodium selenite
Morris water maze
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016422000627

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http://www.sciencedirect.com/science/article/pii/S1319016422000627

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