Biochemical and antigenic characterization of the structural proteins and their post-translational modifications in purified SARS-CoV-2 virions of an inactivated vaccine candidate

ABSTRACTIn the face of COVID-19 pandemic caused by the newly emerged SARS-CoV-2, an inactivated, Vero cell-based, whole virion vaccine candidate has been developed and entered into phase III clinical trials within six months. Biochemical and immunogenic characterization of structural proteins and th...

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Main Authors: Xiao-Yu Zhang, Jing Guo, Xin Wan, Jin-Ge Zhou, Wei-Ping Jin, Jia Lu, Wen-Hui Wang, An-Na Yang, Ding Xiang Liu, Zheng-Li Shi, Zhi-Ming Yuan, Xin-Guo Li, Sheng-Li Meng, Kai Duan, Ze-Jun Wang, Xiao-Ming Yang, Shuo Shen
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1855945