Methylmercury induces inflammatory response and autophagy in microglia through the activation of NLRP3 inflammasome

Methylmercury induces inflammatory response and autophagy in microglia through the activation of NLRP3 inflammasome

Methylmercury (MeHg) is a global environmental pollutant with neurotoxicity, which can easily crosses the blood–brain barrier and cause irreversible damage to the human central nervous system (CNS). CNS inflammation and autophagy are known to be involved in the pathology of neurodegenerative disease...

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Bibliographic Details
Main Authors: Xinyue Li, Kai Ma, Tiantian Tian, Huan Pang, Tianxiang Liu, Meng Li, Jiali Li, Zhixuan Luo, Huiyuan Hu, Shanshan Hou, Jing Yu, Qiaohong Hou, Xiuling Song, Chao Zhao, Haiying Du, Jinhua Li, Zhongjun Du, Minghua Jin
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Environment International
Subjects:
Methylmercury (MeHg)
Microglia
reactive oxygen species (ROS)
NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome
Inflammation
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412024002174

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http://www.sciencedirect.com/science/article/pii/S0160412024002174

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