PLK1 and FoxM1 expressions positively correlate in papillary thyroid carcinoma and their combined inhibition results in synergistic anti‐tumor effects

PLK1 and FoxM1 expressions positively correlate in papillary thyroid carcinoma and their combined inhibition results in synergistic anti‐tumor effects

Polo‐like kinase 1 (PLK1; also known as serine/threonine‐protein kinase PLK1) serves as a central player in cell proliferation, exerting critical regulatory roles in mitotic processes and cell survival. We conducted an analysis of PLK1 protein expression in a large cohort of samples from papillary t...

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Bibliographic Details
Main Authors: Pratheesh Kumar Poyil, Abdul K. Siraj, Divya Padmaja, Sandeep Kumar Parvathareddy, Saravanan Thangavel, Khadija Alobaisi, Roxanne Diaz, Rafia Begum, Wael Haqawi, Saif S. Al‐Sobhi, Fouad Al‐Dayel, Khawla S. Al‐Kuraya
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Molecular Oncology
Subjects:
apoptosis
FoxM1
papillary thyroid cancer
PLK1
stemness
Online Access:https://doi.org/10.1002/1878-0261.13610

Internet

https://doi.org/10.1002/1878-0261.13610

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