CD40 ligand stimulation affects the number and memory phenotypes of human peripheral CD8+ T cells

Abstract Background CD40L is primarily expressed on activated CD4+ T cells and binds to CD40 which is expressed by various cells including dendritic cells, macrophages and B lymphocytes. While CD40-CD40L interaction is known to be direct between B cells and CD4+ T cells which results in proliferatio...

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Bibliographic Details
Main Authors: Haeyoun Choi, Hyun-Joo Lee, Hyun-Jung Sohn, Tai-Gyu Kim
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Immunology
Subjects:
Online Access:https://doi.org/10.1186/s12865-023-00547-2