Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes
Cohesin’s association with and translocation along chromosomal DNAs depend on an ATP hydrolysis cycle driving the association and subsequent release of DNA. This involves DNA being ‘clamped’ by Scc2 and ATP-dependent engagement of cohesin’s Smc1 and Smc3 head domains. Scc2’s replacement by Pds5 abro...
| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
eLife Sciences Publications Ltd
2021-07-01
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| 丛编: | eLife |
| 主题: | |
| 在线阅读: | https://elifesciences.org/articles/67268 |