Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

Cohesin’s association with and translocation along chromosomal DNAs depend on an ATP hydrolysis cycle driving the association and subsequent release of DNA. This involves DNA being ‘clamped’ by Scc2 and ATP-dependent engagement of cohesin’s Smc1 and Smc3 head domains. Scc2’s replacement by Pds5 abro...

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Bibliografiske detaljer
Main Authors: Naomi J Petela, Andres Gonzalez Llamazares, Sarah Dixon, Bin Hu, Byung-Gil Lee, Jean Metson, Heekyo Seo, Antonio Ferrer-Harding, Menelaos Voulgaris, Thomas Gligoris, James Collier, Byung-Ha Oh, Jan Löwe, Kim A Nasmyth
Format: Article
Sprog:English
Udgivet: eLife Sciences Publications Ltd 2021-07-01
Serier:eLife
Fag:
Online adgang:https://elifesciences.org/articles/67268

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