Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

Cohesin’s association with and translocation along chromosomal DNAs depend on an ATP hydrolysis cycle driving the association and subsequent release of DNA. This involves DNA being ‘clamped’ by Scc2 and ATP-dependent engagement of cohesin’s Smc1 and Smc3 head domains. Scc2’s replacement by Pds5 abro...

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מידע ביבליוגרפי
Main Authors: Naomi J Petela, Andres Gonzalez Llamazares, Sarah Dixon, Bin Hu, Byung-Gil Lee, Jean Metson, Heekyo Seo, Antonio Ferrer-Harding, Menelaos Voulgaris, Thomas Gligoris, James Collier, Byung-Ha Oh, Jan Löwe, Kim A Nasmyth
פורמט: Article
שפה:English
יצא לאור: eLife Sciences Publications Ltd 2021-07-01
סדרה:eLife
נושאים:
sister chromatid cohesion
folding
cryo-em
גישה מקוונת:https://elifesciences.org/articles/67268

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