Renal sympathetic denervation attenuates left ventricle hypertrophy in spontaneously hypertensive rats by suppressing the Raf/MEK/ERK signaling pathway

Objective To explore the effect of renal sympathetic denervation (RSD) on left ventricle hypertrophy and the Raf/MEK/ERK signaling pathway in spontaneously hypertensive rats (SHRs). Methods SHRs were divided into SHR, SHR + Sham, SHR + RSD and SHR + U0126 groups, with WKY rats as the baseline contro...

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Bibliographic Details
Main Authors: Bing Xiao, Fan Liu, Ye-Hui Jin, Ya-Qiong Jin, Li Wang, Jing-Chao Lu, Xiu-Chun Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2020.1833022