Cationic Pillar[6]arene Induces Cell Apoptosis by Inhibiting Protein Tyrosine Phosphorylation Via Host–Guest Recognition

Cationic Pillar[6]arene Induces Cell Apoptosis by Inhibiting Protein Tyrosine Phosphorylation Via Host–Guest Recognition

We reported for the first time that cationic pillar[6]arene (cPA6) could tightly bind to peptide polymer (MW~20–50 kDa), an artificial substrate for tyrosine (Tyr) phosphorylation, and efficiently inhibit Tyr protein phosphorylation through host–guest recognition. We synthesized a nanocomposite of b...

Full description

Bibliographic Details
Main Authors: Can-Peng Li, Yu-Xun Lu, Cheng-Ting Zi, Yu-Ting Zhao, Hui Zhao, Ya-Ping Zhang
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
pillar[6]arene
protein tyrosine phosphorylation
molecular recognition
apoptosis
Online Access:https://www.mdpi.com/1422-0067/21/14/4979

Internet

https://www.mdpi.com/1422-0067/21/14/4979

Similar Items