Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1

Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1

Adult mammalian central nervous system (CNS) neurons are unable to regenerate following axonal injury, leading to permanent functional impairments. Yet, the reasons underlying this regeneration failure are not fully understood. Here, we studied the transcriptome and translatome shortly after spinal...

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Bibliographic Details
Main Authors: Wilson Pak-Kin Lou, Alvaro Mateos, Marta Koch, Stefan Klussman, Chao Yang, Na Lu, Sachin Kumar, Stefanie Limpert, Manuel Göpferich, Marlen Zschaetzsch, Christopher Sliwinski, Marc Kenzelmann, Matthias Seedorf, Carlos Maillo, Elena Senis, Dirk Grimm, Radhika Puttagunta, Raul Mendez, Kai Liu, Bassem A. Hassan, Ana Martin-Villalba
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
axon regeneration
translation
polysome profiling
motif analysis
CPEB1
spinal cord injuries
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00445/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00445/full

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