Selective Breeding for Disease-Resistant <i>PRNP</i> Variants to Manage Chronic Wasting Disease in Farmed Whitetail Deer
Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy (TSE) of cervids caused by a misfolded variant of the normal cellular prion protein, and it is closely related to sheep scrapie. Variations in a host’s prion gene, <i>PRNP</i>, and its primary protein struct...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/12/9/1396 |