In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review
Abstract Experimental exposure of healthy volunteers to the T‐cell dependent neoantigen keyhole limpet hemocyanin (KLH) permits the evaluation of immunomodulatory investigational medicinal product (IMP) pharmacology prior to the recruitment of patient populations. Despite widespread use, no standard...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-03-01
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| Series: | Clinical and Translational Science |
| Online Access: | https://doi.org/10.1111/cts.13457 |