Positive interaction between GPER and β-alanine in the dorsal root ganglion uncovers potential mechanisms: mediating continuous neuronal sensitization and neuroinflammation responses in neuropathic pain

Positive interaction between GPER and β-alanine in the dorsal root ganglion uncovers potential mechanisms: mediating continuous neuronal sensitization and neuroinflammation responses in neuropathic pain

Abstract Background The pathogenesis of neuropathic pain and the reasons for the prolonged unhealing remain unknown. Increasing evidence suggests that sex oestrogen differences play a role in pain sensitivity, but few studies have focused on the oestrogen receptor which may be an important molecular...

Full description

Bibliographic Details
Main Authors: Zhenzhen Xu, Wanli Xie, Yiqi Feng, Yanting Wang, Xia Li, Jie Liu, Yue Xiong, Yuyao He, Lu Chen, Guoyang Liu, Qingping Wu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Neuroinflammation
Subjects:
G protein-coupled oestrogen receptor
β-Alanine
Dorsal root ganglion
Neuroinflammation
Neuropathic pain
Online Access:https://doi.org/10.1186/s12974-022-02524-9

Internet

https://doi.org/10.1186/s12974-022-02524-9

Similar Items