Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7

IntroductionPet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is known about the native ligands.MethodsTo provide more information on prospective l...

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Bibliographic Details
Main Authors: Jungki Min, Alexander C. Y. Foo, Scott A. Gabel, Lalith Perera, Eugene F. DeRose, Anna Pomés, Lars C. Pedersen, Geoffrey A. Mueller
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Allergy
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2023.1133412/full