Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts

Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts

Background: Breast cancer bone metastasis and osteoporosis are both severe diseases that seriously threaten human health. These diseases are closely associated with osteolytic lesions. And osteoclasts are the key targets of this pathological process. Given the lack of effective preventive or treatme...

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Bibliographic Details
Main Authors: Tao Li, Guangyao Jiang, Xuantao Hu, Daishui Yang, Tingting Tan, Zhi Gao, Zhuoyuan Chen, Cheng Xiang, Shizhen Li, Zhengxiao Ouyang, Xiaoning Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
punicalin
osteoclast
osteoporosis
osteolysis
NF-κB
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.789552/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.789552/full

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